av DP Schuster · 2007 · Citerat av 60 — Glucose uptake was measured as the rate of [3H]deoxyglucose (DG) uptake. We identified GLUT-1 in mouse neutrophils, but neither GLUT-3 nor GLUT-4 were

av S Willumsen Fransson · 2008 — 'glucose transporter-1' (GLUT-1), som gör det möjligt för specifika substanser att passera över blod-hjärnbarriären [6]. Kring kärlen ligger pericyter, som har.

GLUT1 facilitates the transport of glucose across the plasma membranes of mammalian cells. BACKGROUND: Typical cases of glucose transporter-1 deficiency syndrome (GLUT1-DS)present with early-onset epilepsy. We report symptoms, diagnostic results, andeffects of therapy in two patients diagnosed with GLUT1-DS at the age of 10 and15 years, respectively. This gene provides instructions for producing a protein called the glucose transporter protein type 1 (GLUT1).

Glucose transporter 1

The concomitant induction of the glucose transporter GLUT1 suggests that regulation of glucose transporter GLUT4 cycling by insulin, or regulation of plant growth by auxin or brassinosteroids.1-3 In comparison, we generally assume Glucose enters the cell by glucose transporter (GLUT 2 in rodents, GLUT 1 in humans) and is then phosphorylated for its metabolism through Showing result 1 - 5 of 7 swedish dissertations containing the words Andreas 1. Chromatographic characterization of the human red cell glucose transporter Department of Pharmacotherapy and Translational Research: “The Role of Metabolic Syndrome and Sodium-Glucose Co-Transporter 2 av D RIBEIRO · 2018 — 2.3.1 Decellularized pancreas: the most biomimetic scaffold .. 23 are believed to be the predominant glucose transporters in β cells [29, 30]. At non- För behandling av vuxna med typ 1 diabetes mellitus och BMI ≥ 27 i klassen "sodium glucose transporter 2-inhibitors" (SGLT2-hämmare) Type of. Transport Ac ve or Passive/Mechanism Example. Uniport.

Glucose transporter 1 (GLUT1) expression is regulated by the activity of many genes, including hypoxia‐inducible factor‐1, MYC and PKM2.

ELISA Kit for Glucose Transporter 1 (GLUT1). Enzyme-linked immunosorbent assay for Antigen Detection. Size: 96 tests. Reactivity: Rattus norvegicus (Rat)

Glucose transporter 1 (GLUT1), a ubiquitously expressed glucose transporter, is strongly upregulated after innate and adaptive immune cell activation. Deletion or inhibition of GLUT1 blocked T cell proliferation and effector function, antibody production from B cells and reduced inflammatory responses in macrophages. The SLC2A1 gene encodes the glucose transporter type 1 protein (Glut1), which is responsible for glucose transport across the blood-brain barrier to meet the energy demands of the brain. Pathogenic variants in SLC2A1 disrupt Glut1 protein function and cause GLUT1DS.

Sodium-dependent glucose transporter 1 and glucose transporter 2 mediate intestinal transport of quercetrin in Caco-2 cells June 2020 Food & Nutrition Research 64

Glucose transporter 1 (or GLUT1 ), also known as solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1), is a uniporter protein that in humans is encoded by the SLC2A1 gene. GLUT1 facilitates the transport of glucose across the plasma membranes of mammalian cells. 2015-12-07 · Glucose transporter type 1 deficiency syndrome (GLUT1 deficiency syndrome) is an inherited condition that affects the nervous system. Signs and symptoms generally develop within the first few months of life and may include recurrent seizures ( epilepsy ) and involuntary eye movements.

Kring kärlen ligger pericyter, som har. av E Russo · 2020 · Citerat av 6 — Glut 5 and Glut 2 guide fructose transport into cells where it is metabolized to fructose 1-phosphate by fructokinase (KHK). This reaction induces ATP depletion and European journal of biochemistry 125 (1), 245-249, 1982. 132, 1982. Insulin induces translocation of glucose transporter GLUT4 to plasma membrane caveolae Metformin increases the transport capacity of the membrane glucose transporters GLUT-1 and GLUT-4. Senast uppdaterad: 2017-04-26. Användningsfrekvens: av J Oldgren · 2020 · Citerat av 1 — EFFECTS OF 6 WEEKS OF TREATMENT WITH DAPAGLIFLOZIN, A SODIUM-GLUCOSE COTRANSPORTER 2 INHIBITOR, ON MYOCARDIAL Cat. # IT12688.
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Hereditary deficiency of GLUT-1, insulin -independent transporter, results in decreased glucose transport. Patients manifest with intractable seizures in infancy and a developmental delay. GLUT-1 transporter is expressed in which of the following cell Defects in SLC2A1 are the cause of glucose transporter type 1 deficiency syndrome (GLUT1DS) [MIM:606777]; also known as blood-brain barrier glucose transport defect. This disease causes a defect in glucose transport across the blood-brain barrier. It is characterized by infantile seizures, delayed development, and acquired microcephaly.

1 It is expressed predominantly in the kidney where it reabsorbs approximately 90% of the filtered glucose Several studies have found that increased glucose transporter‑1 (GLUT‑1) expression is associated with radioresistance. Recently, the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) pathway was reported to be involved in the control of GLUT‑1 trafficking and activity. Aim. To assess the efficacy and safety of combination therapy with a glucagon‐like peptide‐1 receptor agonist (GLP‐1 RA) and a sodium‐glucose co‐transporter‐2 inhibitor (SGLT2i) in patients with type 2 diabetes.
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Created using PowToon.CO An overview of the two families of glucose transporters, their modes of transportation, and their function in the body. There are two mechanisms for glucose transport across cell membranes. In the intestine and renal proximal tubule, glucose is transported against a concentration gradient by a secondary active transport mechanism in which glucose is cotransported with sodium ions. In all other cells, glucose transport is mediated by one or more of the members of the closely related GLUT family of glucose Glucose transporter-1 expression in renal cell carcinoma and its correlation with hypoxia inducible factor-1 alpha. Lidgren A(1), Bergh A, Grankvist K, Rasmuson T, Ljungberg B. Author information: (1)Department of Surgical and Perioperative Sciences, Umeå University, Umeå, Sweden.

Sökning: "glucose transporter 4". Visar resultat 1 - 5 av 33 avhandlingar innehållade orden glucose transporter 4. 1. Quantitation, Purification and Reconstitution

Huvudmedlemmen bland natrium-glukostransportproteinerna. Proteinet uttrycks ELISA Kit for Glucose Transporter 1 (GLUT1).

Glucose Transporter 1 GLUT1 was the first glucose transporter to be cloned and is undoubtedly one of the most intensively studied of all membrane transport proteins. The amino acid sequence of GLUT1 is highly conserved and 98% identity exists between the sequences of human and rat GLUT1 and 97% identity between the sequences of human and mouse, rabbit, or pig. Glucose transporter-1 (GLUT-1) mediates the transport of glucose across the cellular membrane. Its elevated levels and/or activation have been shown to be associated with malignancy. The aim of this study was to investigate GLUT-1 expression in pulmonary neuroendocrine carcinomas. 2021-03-10 · Glucose transporter-1 (GLUT1) deficiency syndrome: diagnosis and treatment in late childhood. Gramer G(1), Wolf NI, Vater D, Bast T, Santer R, Kamsteeg EJ, Wevers RA, Ebinger F. Author information: (1)Division of Metabolic Disorders, Department of General Paediatrics, Centre for Paediatric and Adolescent Medicine, Heidelberg, Germany.